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The FLOW trial notably demonstrated a reduction in the risk of major adverse cardiovascular events, death from cardiovascular causes and all-cause mortality with semaglutide in adults with CKD and T2D, with prespecified analyses suggesting that these outcomes were consistent in patients across BMI groups and with/without prior SGLT2i use [9]

Patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use tirzepatide, as GLP-1 receptor agonists have been associated with thyroid C-cell tumors in rodent studies

The condition is called: Idiopathic : no identified cause Intracranial hypertension : high pressure inside the skull Pseudotumor cerebri : old name meaning "false brain tumor" (mimics tumor symptoms) Symptoms Headache Most common symptom Often daily, throbbing Worse in morning Worse with straining, coughing, bending May improve after vomiting May be triggered by lying down Visual Symptoms Transient visual obscurations : brief (seconds) dimming or graying of vision Often triggered by position change or straining Visual field loss : may be gradual and unnoticed Blurred vision Double vision : from sixth nerve palsy Other Symptoms Pulsatile tinnitus : whooshing sound in ears synchronized with heartbeat Neck and shoulder pain Nausea Cognitive difficulties ("brain fog") Who Gets IIH

10.1007/s00167-009-0828-7 Knee Surg

Lancet Diab Endocrinol